Development of Intestinal Intraepithelial and Intrathymic and Extrathymic Tyrosine Phosphatase for Cytolytic Activities Differential Requirements of CD45 Protein
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منابع مشابه
Development of intestinal intraepithelial lymphocytes, NK cells, and NK 1.1+ T cells in CD45-deficient mice.
The transmembrane protein tyrosine phosphatase CD45 is differentially required for the development and function of B, T, and NK cells, with mice partially deficient for CD45 having a significant inhibition of T cell, but not NK or B cell, development. CD45-mediated signaling has also been implicated in the development of intrathymic, but not extrathymic, intestinal intraepithelial T lymphocytes...
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